Drug intelligence / Profile preview

methyl n-[(2s,3r)-3-amino-2-hydroxy-3-(4-methylphenyl)propanoyl]-d-alanyl-d-leucinate

Development stage
Unknown
Modality
Small Molecules
01

Overview

Methyl n-[(2s,3r)-3-amino-2-hydroxy-3-(4-methylphenyl)propanoyl]-d-alanyl-d-leucinate is a synthetic peptide derivative. It is known to be a potent inhibitor of HIV-1 protease, designed as a peptidomimetic compound. While studied for its antiviral potential, it appears to be primarily a research compound or a lead structure in the development of HIV protease inhibitors, rather than a clinically approved or widely developed drug.

Other names
methyl (2r)-2-[(2s)-2-[(2s,3r)-3-amino-2-hydroxy-3-(4-methylphenyl)propanamido]propanamido]-4-methylpentanoated-leucine, n-[(2s,3r)-3-amino-2-hydroxy-3-(4-methylphenyl)-1-oxopropyl]-l-alanyl-, methyl estermethyl n-[((2s,3r)-3-amino-2-hydroxy-3-(4-methylphenyl)propanoyl)]
02

Targets

PR (Progesterone receptor)

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